A Outline of Minamata Disease
4. Lesions of Damaged by Methylmercury

 
Control

Horizontal section of right hemisphere of cerebrum

51 years old, male,

Cerebrum weight 1,380 g

 
Minamata disease patient

Horizontal section of right hemisphere of cerebrum

Case of acute onset and long-term survival 23 years old, female

Cerebrum weight 775 g

   
A horizontal section of right hemisphere of cerebrum showing lesions (unstained and strongly atrophic) in the calcarine cortex of visual cortex (↑↑), the temporal transverse gyrus containing auditory center (↑).

 

Control

Horizontal section of right hemisphere of cerebrum

51 years old, male

 

Minamata disease patient

Horizontal section of right hemisphere of cerebrum

Case of acute onset and long-term survival 23 years old, female

   
Severe atrophy of the hemisphere of the cerebellum. Total loss of granule cells in the cerebellum except vermis (↑)