National Institute For Minamata Disease

[Original articles（Peer-reviewed article）]

Sakamoto M, Haraguchi K, Tatsuta N, Marumoto M, Yamamoto M, Nakamura M: Breast milk contribution to tissue mercury levels in rat pups examined by cross-fostering at birth. Environ Res., 2022; 208: 112772. https://doi.org/10.1016/j.envres.2022.112772
Haraguchi K, Matsuyama A, Akagi H: Simple and sensitive method for the determination of methylmercury in hair using thin-layer chromatography with thermal decomposition gold amalgamation atomic absorption spectrophotometry. Anal. Sci., 2022; 38: 215-221.
https://doi.org/10.2116/analsci.21P105
Sakamoto M, Haraguchi K, Tatsuta N, Nakai K, Nakamura M, Murata K: Plasma and red blood cells distribution of total mercury, inorganic mercury, and selenium in maternal and cord blood from a group of Japanese women. Environ. Res., 2021 196. 110896.
https://doi.org/10.1016/j.envres.2021.110896
Haraguchi K, Sakamoto M, Matsuyama A, Yamamoto M, Dang T H, Nagasaka H, Uchida K, Ito Y, Kodamatani H, Horvat M, Chan H M, Rand M, Cirtiu C M, Kim B G, Nielsen F, Yamakawa A, Mashyanov N, Panichev N, Panova E, Watanabe T, Kaneko N, Yoshinaga J, Herwati R F, Suoth A E, Akagi H: Development of human hair reference material supporting the biomonitoring of methylmercury. Anal. Sci., 2020; 36: 561-566.
https://doi.org/10.2116/analsci.19SBP07
Kim B G, Hong Y S, Haraguchi K, Sakamoto M, Lim H J, Seo J W, Kim Y M: Comparative screening analytic methods for elderly of blood methylmercury concentration between two analytical institutions. Comput. Math. Method M., 2018; Article ID 2509413, 5 pages.
https://doi.org/10.1155/2018/2509413
Tokunaga Y, Haraguchi K, Hachiri M, Tsutsumi H, Ichinomiya M: Poppulation dynamics of Ruditapes philippinarum on the Sashiki Tidal Flats in Yatsushiro Bay, western Japan. J. Jpn. Soc. Shiranuikai Kumagawa Reg. Stud., 2015；9: 21-35. (in Japanese with English abstract)
Haraguchi K, Ohwada K: Atmospheric wet deposition in nitrogen and phosphorus loads to Yatsushiro Bay, Japan. Water and Waste, 2012; 54: 367-375. (in Japanese)
Haraguchi K, Ohwada K: Relation between Kuma River discharge and volume transport driven by the vertical circulation in the northern Yatsushiro Bay. J. Jpn. Soc. Shiranuikai Kumagawa Reg. Stud., 2011；5: 15-20. (in Japanese with English abstract)
Haraguchi K, Sakurada K, Ohwada K: Evaluation of benthic nutrient fluxes and their importance in the pelagic nutrient cycles in Yatsushiro Bay. Water and Waste, 2011; 53: 205-212. (in Japanese)
https://ci.nii.ac.jp/naid/40018714139
Haraguchi K, Ohwada K: Fresh water input loads of nitrogen and phosphorous to Yatsushiro Bay, Japan. Water and Waste, 2011; 53: 125-133. (in Japanese)
https://ci.nii.ac.jp/naid/40018707594
Haraguchi K, Yamamoto T, Shimizu Y, Chiba S, Nagao M: Effects of phytoplankton vertical migration on the formation of oxygen depleted water in a shallow coastal sea. Estuar. Coast. Shelf. Sci., 2010; 86: 441-449.
https://doi.org/10.1016/j.ecss.2009.08.019
Yamamoto T, Sasada S, Haraguchi K: An artificial midlayer seafloor-Evaluation of reducing sinking particulate load from suspended oyster culture seafloor from an initial half-year observations. Nippon Suisan Gakkaishi, 2009; 75: 834-843 (in Japanese with English abstract).
https://doi.org/10.2331/suisan.75.834
Haraguchi K, Yamamoto T, Katayama T, Matsuda O: Carbon flow through the food web established on an artificial fish reef. Nippon Suisan Gakkaishi, 2009; 75: 810-818 (in Japanese with English abstract)
https://doi.org/10.2331/suisan.75.810
Haraguchi K, Yamamoto T: Measurement of benthic photosynthesis on the sublittoral seafloor by the in situ microelectrode method and oxygen flux method. Bull. Coast. Oceanogr., 2009; 47: 43-49 (in Japanese with English abstract).
https://doi.org/10.32142/engankaiyo.47.1_43
Anggara, G A K, Chiba S, Yamagata Y, Shimizu Y, Haraguchi K: Numerical model on the material circulation for coastal sediment in Ago Bay, Japan. J. Marine Sys., 2009; 77: 45-60.
https://doi.org/10.1016/j.jmarsys.2008.11.006
Asaoka S, Yamamoto K, Haraguchi K, Yamamoto T: Effects of granulated coal ash as a sediment amendment on benthic microalgae and microbial communities in the sediment. Water and Waste, 2009; 51: 237-244
https://ci.nii.ac.jp/naid/40016497171
Yamamoto T, Hashimoto T, Matsuda O, Go A, Nakaguchi K, Haraguchi K: Comparison of sediment quality between Hiroshima Bay and Suo Nada: Special reference to the seasonal variations of sediment quality parameters and their relationships. Nippon Suisan Gakkaishi, 2008; 74: 1037-1042. (in Japanese with English abstract)
https://doi.org/10.2331/suisan.74.1037
Anggara, G A K, Chiba S, Yamagata Y, Shimizu Y, Haraguchi K: Modeling early diagenesis of sediment in Ago Bay Japan, A comparison of steady state and dynamic calculations. Ecol. Model., 2008; 215: 40-54.
https://doi.org/10.1016/j.ecolmodel.2008.02.025
Haraguchi K, Yamamoto T, Katayama T, Yamagata Y, Matsuda O: Enhancement of aerobic decomposition of organic matter from aquaculture by an artificial midlayer seafloor. Nippon Suisan Gakkaishi, 2008; 74: 424-431. (in Japanese)
https://doi.org/10.2331/suisan.74.429
Haraguchi K, Kokubu H, Okumura H, Yamamoto T: Nitrogen Removal by Fisheries in Ago Bay, Japan. Aqua. Sci., 2007; 55: 653-654. (in Japanese with English abstract)
https://doi.org/ 10.11233/aquaculturesci1953.55.653
Haraguchi K, Taniguchi A: Effect of simultaneous enrichment of dephosphorization steelmaking slag and treated municipal sewage on growth of coastal phytoplankton assemblages. Tetsu-to-Hagane, 2003; 89: 430-437. (In Japanese with English abstract)
https://doi.org/10.2355/tetsutohagane1955.89.4_430
Haraguchi K, Suzuki K, Taniguchi A: Effect of steelmaking slag addition on growth of marine phytoplankton. ISIJ Int., 2003; 43: 1461-1468.
https://doi.org/10.2355/isijinternational.43.1461
Haraguchi K, Ando T, Sato M, Kawaguchi C, Tomiyasu T, Horvat M, Akagi H: Detection of localized methylmercury contamination by use of the mussel adductor muscle in Minamata Bay and Kagoshima Bay, Japan. Sci. Total Environ., 2000; 261: 75-89.
https://doi.org/10.1016/S0048-9697(00)00626-4
Akagi H, Haraguchi K, Yoshihide K, Malm O, Branches F J P, Guimares J R J: Exposure of aboriginal pepole to methylmercury due to gold mining in Amazon, Brazil. J. Environ. Sci., 2000; 12: 45-50.
Eto K, Takizawa Y, Akagi H, Haraguchi K, Asano S, Takahata N, Tokunaga H: Differential diagnosis between organic and inorganic mercury poisoning in human cases-the pathologic point of view. Toxicol. Pathol., 1999; 27: 664-671.
https://doi.org/10.1177/019262339902700608
Sato M, Haraguchi K, Ando T, Tomiyasu T, Akagi H: Distribution of total mercury and methylmercury in tissues of the mussel Mytilus gllaoprovincialis. Environ. Sci., 1997; 5: 225-237.
Akagi H, Malm O, Branches F J P, Kashima Y, Guimares J R J, Oliveria R B, Haraguchi K, Pheiffer W C, Takizawa Y, Kato H: Human exposure to mercury due to goldmining in the Tapajos River basin, Amazon, Brazil: speciation of mercury in human hair, blood and urine. Water Air Soil Pollut., 1995; 80: 85-94.
https://doi.org/10.1007/BF01189656
Tanaka T, Higashi A, Asakawa M, Matsuda I, Haraguchi K, Akagi H: Contents of lead, cadmium and mercury in breast milk of Japanese lactating women. Biomed. Res. Trace Elem., 1995; 6: 155-156. (in Japanese)
https://ci.nii.ac.jp/naid/10028280241/

[Original articles（Non-reviewed article）]
Yamamoto T, Asaoka S, Haraguchi K: Effects of magnesium oxide-added polyethylene-coated steel wire on the growth of attached marine diatom Nitzschia sp. J. Grad. Sch. Biosp. Sci. Hiroshima Univ., 2008; 47: 53-59. (In Japanese with English abstract)
http://doi.org/10.15027/39868
Taniguchi A, Haraguchi K, Nakamura Y, Arita K, Umiguchi Y, Nishino Y: A possible scenario for environmental remediation in coastal waters by use of phytoplankton and waste materials. Tohoku J. Agri. Res., 2003; 54: 53-63.
https://ci.nii.ac.jp/naid/110000992123

[Other Publications]
Haraguchi K: A method for the determination of mercury in urine for elemental mercury exposure assessment in ASGM (in Japanese). Bunseki, 2018; 2: 72.
Haraguchi K: Development of human hair reference material supporting biomonitoring of methylmercury (in Japanese). Prospect and Topics, 2017; 66: 10.
Haraguchi K, Matsuyama A: Technical transfer and cooperation for mercury analysis. Environ. Sol. Tech., 2015; 6: 13-15. (in Japanese)
Ohwada K, Haraguchi K, Morishita K, Umeda K: Transplantation as a method for restoring the seagrass: Improving seagrass transplantation in the subtidal zone. J. Jpn. Soc. Shiranuikai Kumagawa Reg. Stud., 2012; 5: 15-20. (in Japanese)
Anggara, G A K, Chiba S, Yamagata Y, Shimizu Y, and Haraguchi K: Application of the early diagenesis model to Ago Bay sediment, Japan: Comparison of the sediment characteristics between two observation sites. Glob. Environ. Eng. Res., 2008: 16: 51-61.
https://www.jstage.jst.go.jp/browse/proge1998
Haraguchi K, Matsuda T, Yamagata Y, Chiba S: Seasonal and long-term trends in the water quality of Ago Bay, Japan. Aquabio.,. 2008; 176: 272-282. (in Japanese with English abstract)
https://ci.nii.ac.jp/naid/40016132905
Yamagata Y, Chiba S, Haraguchi K, Shimizu Y, Momoshima N, Hisano S and Matsuwo M: Characteristics and deterioration phenomena of marine sediments in Ago Bay. Aquabio., 2008; 176: 283-293. (In Japanese with English abstract)
https://ci.nii.ac.jp/naid/40016132906
Matsuda T, Chiba S, Tanimura A, Hata N. Haraguchi K: Characteristics of primary productivity, phytoplankton and zooplankton in Ago Bay. Aquabio., 2008.;176: 328-334. (in Japanese with English abstract)
https://ci.nii.ac.jp/naid/40016132910
Haraguchi K: Enhancement of aerobic decomposition of organic matter from aquaculture by an artificial midlayer seafloor. Mie Net. 2007; 78: 17. (in Japanese)
Haraguchi K, Ito H, Hiratsuka M, Nakayama E, Taniguchi A: Possible ocean enrichment with steelmaking slags in HNLC and subtropical regions. In: CO2 Fixation Study Group (Eds.), Enhancement of photosynthetic CO2 fixation by marine phytoplankton with steelmaking slag as a nutrient source. The Iron and Steel Institute of Japan, Tokyo. 2001; 30-33. (in Japanese)
Arita K, Haraguchi K, Taniguchi A: Availability of Steelmaking Slag as a Source of Essential Elements for Phytoplankton. In: CO2 Fixation Study Group (Eds.), Enhancement of photosynthetic CO2 fixation by marine phytoplankton with steelmaking slag as a nutrient source. The Iron and Steel Institute of Japan, Tokyo. 2001; 24-25. (in Japanese)
Taniguchi A, Haraguchi K: Possible ocean enrichment with steelmaking slags. Marine Science Monthly, 2002; 34: 172-176. (In Japanese)
https://ci.nii.ac.jp/naid/40004805393

[Book]
Haraguchi K, Yamamoto T: Microphytobenthic productivity and biomass in sublittoral sediments. In: Taniguchi A, Sasaki H (Eds.), Marine plankton ecology, Seizando Press, Tokyo, 2008; 299-321. (in Japanese)
https://ci.nii.ac.jp/naid/110007055467

[Patents]
Yamamoto T, Haraguchi K, Himeno S: Method of culturing attached algae, P2010-51292A
Haraguchi K: Oxygen consumption rate measuring device on the seafoor, P2007-120992A
Haraguchi K, Tawara M, Katayama T: Aerobic decomposition device of organic matter, P2007-143494A（Patent No.4444914）．

[Invited lectures]
Haraguchi K: Laboratory proficiency testing on mercury analysis. UNEP/ROAP Project for promoting the Minamata Convention on Mercury: Asia-Pacific Annual Webinar on Mercury Science 2021, Web meeting, 2021. 10.
Haraguchi K: Human biomonitoring for mercury exposure and analytical quality control. Environmental Science Seminar, Tokyo, 2020. 1.
Haraguchi K: Human Biomonitoring for Mercury –state of the art. WHO SE Regional Workshop: Health Sector Involvement in Implementation of the Minamata Convention on Mercury, Bangkok, 2017. 7.
Haraguchi K: Human biomonitoring for mercury exposure–including hair sampling demonstration. WHO WP Regional Workshop: Health Sector Involvement in Implementation of the Minamata Convention on Mercury, Minamata, 2017. 6.
Haraguchi K: Analytical indicators, risks and benefits of monitoring and analysis. International Seminar of Mercury, Montevideo, 2017. 3.
Haraguchi K: Mercury in the environment and its effects on health. Case of Minamata. International Seminar of Mercury, Montevideo, 2017. 3.
Haraguchi K: Technical transfer and cooperation for mercury analysis by NIMD. JICA Volunteer and Professional Participants Meeting, Kumamoto, 2016. 12.
Haraguchi K: Effects of benthic maicroalgae on the formation of oxygen depleted water. 5th Environmental Dynamics and management Seminar, Higashi-Hiroshima, 2008. 12.
Haraguchi K, Yamamoto T: Measurement of benthic photosynthesis on the sublittoral seafloor. Annual Coastal Oceanographic Research Symposium, Kure, 2008. 9.
Taniguchi A, Haraguchi K: A possible scenario for environmental remediation in coastal waters by use of waste materials．Ocean Research Institute Symposium, Tokyo, 2000. 12.

[Oral Presentations（2015~）]
Haraguchi K, Sakamoto M, Matsuyama A, Yamamoto M, Nagasaka H, Yoshinaga J: Development of human urine and hair reference materials for human biomonitoring of mercury. 14th ICMGP, Krakow, 2019. 9.
Haraguchi K: Simplified method for determination of mercury and new reference materials for human biomonitoring. NIMD Forum 2018, Minamata, 2018. 11.
Haraguchi K, Sakamoto Nagasaka H, Uchida K, Ito Y, Yoshinaga J: Development of human urine reference material supporting biomonitoring of elemental mercury. 67th JSAC, Sendai, 2018. 9. (in Japanese)
Haraguchi K, Sakamoto M, Yamamoto M, Matsuyama A, Dang T H, Nagasaka H, Yamakawa A, Sano T. Yoshinaga J: Development of human hair reference material supporting biomonitoring of methylmercury. 66th JSAC, Tokyo, 2017. 9. (in Japanese)
Haraguchi K, Sakamoto M, Yamamoto M, Matsuyama A, Hung D T, Yamakawa A, Sano T, Yoshinaga J: Development of human hair reference material supporting biomonitoring of methylmercury. 13th ICMGP, Providence, 2017. 7.
Haraguchi K, Matsuyama A, Akagi H: Simple method for the determination of MMHg using dithizone extraction/TLC/TDA AAS. 65th JSAC, Sapporo, 2016. 9. (in Japanese)
Haraguchi K, Matsuyama A: Development of a simple method for the determination of monomethyl mercury in least developed countries. Parea exhibition in Kumamoto city international center, Kumamoto, 2015. 7.