TOP > DEPARTMENTS > DEPARTMENT OF INTERNATIONAL AFFAIRS AND RESEARCH

Koichi Haraguchi, Ph.D.

Department of International Affairs and Research
Mercury Analysis Technique Section
Senior Researcher

Accurate mercury concentration of human and environmental samples is indispensable for the success of mercury pollution control. It also plays an important role in the achievement of “Identification and characterization of mercury pollution (Articles 8, 9 and 12)”, “Implement plans for mercury pollution (Article 20)” and “Effectiveness evaluation of risk management (Articles 22)” of the Minamata Convention on Mercury. For most developing countries, Artisanal and Small-Scale Gold Mining (ASGM) is the largest source of mercury pollution. Our laboratory is dedicated to development mercury analytical techniques to meet a demand for the countries are facing increased health and environmental risks linked to mercury exposure. In addition, we focus on the development of reference materials for evaluating the accuracy of Hg analysis for human biomonitoring. These are part of the MOYAI initiatives aimed at promoting to support least developed countries’ (LDCs’) with their efforts in mercury monitoring.


新聞記事
Development of human hair reference material supporting biomonitoring of
methylmercury. Reprinted by courtesy of NIKKAN KOGYO NEWSPAPER, p23.
(2017, September 6 Published)


The ISO/IEC 17025 standard (general requirements for the competence of testing and calibration laboratories) is one of the main standards used for testing and calibration laboratories for their quality system. We were accredited to the standard for testing laboratories of Hg in human hair and urine. The purpose of accreditation is to improve our data quality and to provide certified reference materials, such as specified property values with associated uncertainties and trace abilities. We slightly modified the “Mercury Analysis Manual (MOE 2004)”, improving the detection limit for low concentration urine samples. After review by the accreditation organization, we were accredited to the ISO/IEC 17025 laboratory certification in February 2018. We remain committed to making further contributions in addressing the accuracy of the assessment of human and environmental exposure to mercury compounds by improving and further developing the mercury analysis as a testing laboratory.

NHK写真
Laboratory accreditation of ISO/IEC 17025 (Feb 2018)


Subjects of study and affair
[Project research]
  • Development of a simple method for the determination of monomethyl mercury in least developed countries (representative)
[Committee]
Chemicals control committee
ISO Committee
Equipment Maintenance Committee
Study group
  • International Contribution Group
Research achievements
[Research Result (Publication)]
Original Paper
Comparative screening analytic methods for elderly of blood methylmercury concentration between two analytical institutions
Presenter: Kim B.G., Hong Y.S., Haraguchi K., Sakamoto M., Lim H.J., Seo J.W., Kim Y.M.
Title: Computational and Mathematical Methods in Medicine, Article ID 2509413 (2018)

Review
A method for the determination of mercury in urine for elemental mercury exposure assessment in ASGM (in Japanese)
Presenter: Haraguchi K.
Title: Bunseki, 2: 72 (2018)

Other Publications
Development of human hair reference material supporting biomonitoring of methylmercury (in Japanese)
Presenter: Haraguchi K.
Title: Prospect and Topics, 66: 10 (2017)

Review
Technical transfer and cooperation for mercury analysis (in Japanese)
Presenter: Haraguchi K., Matsuyama A.
Title: Environmental Solution Technology. 14: 4-8 (2015)

Original Paper
Poppulation dynamics of Ruditapes philippinarum on the Sashiki Tidal Flats in Yatsushiro Bay, western Japan (in Japanese with English abstract)
Presenter: Tokunaga, Y., Haraguchi K., Hachiri M., Tsutsumi H., Ichinomiya M.
Title: Journal of Japanese Society of Shiranuikai & Kumagawa Regional Studies, 5: 15-20 (2015)

Original Paper
Atmospheric wet deposition in nitrogen and phosphorus loads to Yatsushiro Bay, Japan (in Japanese)
Presenter: Haraguchi K., Ohwada K.
Title: Water and Waste, 54: 367-375 (2012)

Other Publications
Transplantation as a method for restoring the seagrass: Improving seagrass transplantation in the subtidal zone (in Japanese)
発表者: Ohwada K., Haraguchi K., Morishita K., Umeda K.
掲載誌: Journal of Japanese Society of Shiranuikai & Kumagawa Regional Studies, 5: 15-20 (2012)

Original Paper
Relation between Kuma River discharge and volume transport driven by the vertical circulation in the northern Yatsushiro Bay (in Japanese with English abstract)
Presenter: Haraguchi K., Ohwada K.
Title: Journal of Japanese Society of Shiranuikai & Kumagawa Regional Studies, 5: 15-20 (2011)

Original Paper
Evaluation of benthic nutrient fluxes and their importance in the pelagic nutrient cycles in Yatsushiro Bay (in Japanese)
Presenter: Haraguchi K., Sakurada K., Ohwada K.
Title: Journal of Water and Waste, 53: 205-212 (2011)

Original Paper
Fresh water input loads of nitrogen and phosphorous to Yatsushiro Bay, Japan.Journal of Water and Waste (in Japanese)
Presenter: Haraguchi K., Ohwada K.
Title: Journal of Water and Waste, 53: 125-133 (2011)

Original Paper
Effects of phytoplankton vertical migration on the formation of oxygen depleted water in a shallow coastal sea
Presenter: Haraguchi K., Yamamoto T., Shimizu Y., Chiba S., Nagao M.
Title: Estuarine, Coastal and Shelf Science. 86: 441-449 (2010)

Original Paper
An artificial midlayer seafloor-Evaluation of reducing sinking particulate load from suspended oyster culture seafloor from an initial half-year observations (in Japanese with English abstract)
Presenter: Yamamoto, T., Sasada S., Haraguchi K.
Title: Nippon Suisan Gakkaishi, 75: 834-843 (2009)

Original Paper
Carbon flow through the food web established on an artificial fish reef (in Japanese with English abstract)
Presenter: Haraguchi, K. Yamamoto T., Katayama T. ,Matsuda O.
Title: Nippon Suisan Gakkaishi, 75: 810-818 (2009)

Original Paper
Measurement of benthic photosynthesis on the sublittoral seafloor by the in situ microelectrode method and oxygen flux method. Bulletin on Coastal (in Japanese with English abstract) Presenter: Haraguchi, K. Yamamoto T.
Title: Oceanography, 47: 43-49 (2009)

Original Paper
Numerical model on the material circulation for coastal sediment in Ago Bay Japan
Presenter: Anggara, G.A.K., Chiba S., Yamagata Y., Shimizu Y., Haraguchi K.
Title: Journal of Marine Systems, 77: 45-60 (2009)

Original Paper
Effects of granulated coal ash as a sediment amendment on benthic microalgae and microbial communities in the sediment (in Japanese with English abstract)
Presenter: Asaoka, S., Yamamoto K., Haraguchi K., Yamamoto T.
Title: Journal of Water and Waste, 51: 237-244 (2009)

Original Paper
Comparison of sediment quality between Hiroshima Bay and Suo Nada: Special reference to the seasonal variations of sediment quality parameters and their relationships (in Japanese with English abstract)
Presenter: Yamamoto, T., Hashimoto T., Matsuda O., Go A., Nakaguchi K., Haraguchi K.
Title: Nippon Suisan Gakkaishi, 74: 1037-1042 (2008)

Original Paper
Application of the early diagenesis model to Ago Bay sediment, Japan: Comparison of the sediment characteristics between two observation sites
Presenter: Anggara, G.A.K., Chiba S., Yamagata Y., Shimizu Y., Haraguchi K.
Title: Global Environment Engineering Research, 16: 51-61 (2008)

Original Paper
Modeling early diagenesis of sediment in Ago Bay Japan, A comparison of steady state and dynamic calculations
Presenter: Anggara, G.A.K., Chiba S., Yamagata Y., Shimizu Y., Haraguchi K.
Title: Ecological Modelling, 215: 40-54 (2008)

Original Paper
Enhancement of aerobic decomposition of organic matter from aquaculture by an artificial midlayer seafloor (in Japanese)
Presenter: Haraguchi K., Yamamoto T., Katayama T., Yamagata Y., Matsuda O.
Title: Nippon Suisan Gakkaishi 74: 424-431 (2008)

Book
Microphytobenthic productivity and biomass in sublittoral sediments (in Japanese)
Presenter: Haraguchi K., Yamamoto T.
Title: In: A. Taniguchi and H. Sasaki (Eds.), Marine plankton ecology. Seizando Press, Tokyo, 299-321 (2008)

Review
Seasonal and long-term trends in the water quality of Ago Bay, Japan (in Japanese with English abstract)
発表者: Haraguchi K., Matsuda T., Yamagata Y., Chiba S.
Title: Aquabiology 176: 272-282 (2008)

Review
Characteristics and deterioration phenomena of marine sediments in Ago Bay (in Japanese with English abstract)
Presenter: Yamagata Y., Chiba S., Haraguchi K., Shimizu Y., Momoshima N., Hisano S., Matsuwo M. Title: Aquabiology 176: 283-293 (2008)

Review
Characteristics of primary productivity, phytoplankton and zooplankton in Ago Bay (in Japanese with English abstract)
Presenter: Matsuda T., Chiba S., Tanimura A., Hata N., Haraguchi K.
Title: Aquabiology 176: 328-334 (2008)

Review
Effects of magnesium oxide-added polyethylene-coated steel wire on the growth of attached marine diatom Nitzschia sp. (in Japanese with English abstract)
Presenter: Yamamoto T. Asaoka S., Haraguchi K.
Title: Journal of Graduate School of Biosphere Science Hiroshima University, 47: 53-59 (2008)

Original Paper
Nitrogen Removal by Fisheries in Ago Bay, Japan (in Japanese with English abstract) Presenter: Haraguchi K., Kokubu H., Okumura H., Yamamoto T.
Title: Aquaculture Science 55: 653-654 (2007)

Other Publications
Enhancement of aerobic decomposition of organic matter from aquaculture by an artificial midlayer seafloor
Presenter: Haraguchi K.
Title: Mie Net. 78: 17 (2007)

Original Paper
Effect of simultaneous enrichment of dephosphorization steelmaking slag and treated municipal sewage on growth of coastal phytoplankton assemblages (in Japanese with English abstract)
Presenter: Haraguchi K., Taniguchi, A.
Title: Tetsu-to-Hagane, 89: 430-437 (2003)

Original Paper
Effect of steelmaking slag addition on growth of marine phytoplankton
Presenter: Haraguchi K., Suzuki K., Taniguchi, A.
Title: ISIJ International, 43: 1461-1468 (2003)

Review A possible scenario for environmental remediation in coastal waters by use of phytoplankton and waste materials
Presenter: Taniguchi, A., Haraguchi K., Nakamura Y., Arita K., Umiguchi Y., Nishino Y.
Title: Tohoku Journal of Agricultural Research, 54: 53-63 (2003)

Review
Possible ocean enrichment with steelmaking slags (In Japanese)
Presenter: Taniguchi, A., Haraguchi K.
Title: Marine Science Monthly, 34: 172-177 (2002)

Review
Possible ocean enrichment with steelmaking slags in HNLC and subtropical regions (In Japanese) Presenter: Haraguchi K., Ito H., Hiratsuka M., Nakayama E., Taniguchi A.
Title: CO2 Fixation Study Group (Eds.), Enhancement of photosynthetic CO2 fixation by marine phytoplankton with steelmaking slag as a nutrient source. The Iron and Steel Institute of Japan, Tokyo. 30-33 (2001)

Review
Availability of Steelmaking Slag as a Source of Essential Elements for Phytoplankton (In Japanese)
Presenter: Arita, K., Haraguchi K., Taniguchi A.
Title: CO2 Fixation Study Group (Eds.), Enhancement of photosynthetic CO2 fixation by marine phytoplankton with steelmaking slag as a nutrient source. The Iron and Steel Institute of Japan, Tokyo. 24-25 (2001)

Original Paper
Detection of localized methylmercury contamination by use of the mussel adductor muscle in Minamata Bay and Kagoshima Bay, Japan
Presenter: Haraguchi K., Ando T., Sato M., Kawaguchi C., Tomiyasu T., Horvat M., Akagi H. Title: The Science of the Total Environment, 261: 75-89 (2000)

Original Paper
Exposure of aboriginal pepole to methylmercury due to gold mining in Amazon, Brazil Presenter: Akagi, H., Haraguchi K., Yoshihide K., Malm O., Branches F.J.P., Guimares J.R.J. Title: Journal of Environmental Sciences, 12: 45-50 (2000)

Original Paper
Differential diagnosis between organic and inorganic mercury poisoning in human cases- the pathologic point of view
Presenter: Eto, K., Takizawa Y., Akagi H., Haraguchi K.), Asano S., Takahata N., Tokunaga H. Title: Toxicologic Pathology, 27: 664-671 (1999)

Original Paper
Distribution of total mercury and methylmercury in tissues of the mussel Mytilus gllaoprovincialis
Presenter: Sato, M., Haraguchi K., Ando T., Tomiyasu T., Akagi H.
Title: Environmental Science, 5: 225-237 (1997)

Original Paper
Human exposure to mercury due to goldmining in the Tapajos River basin, Amazon, Brazil: speciation of mercury in human hair, blood and urine. Water
Presenter: Akagi, H. , Malm O., Branches F.J.P., Kashima Y., Guimares J.R.J., Oliveria R.B., Haraguchi K., Pheiffer W.C., Takizawa Y., Kato H.
Title: Air and Soil Pollution, 80: 85-94 (1995)

Original Paper
Contents of lead, cadmium and mercury in breast milk of Japanese lactating women (In Japanese) Presenter: Tanaka T., Higashi A., Asakawa M., Matsuda I., Haraguchi K., Akagi H.
Title: Biomedical Research on trace elements, 6 (3): 155-156 (1995)

[Research Result (Presentation)]
Research Lecture
Human biomonitoring for mercury exposure?including hair sampling demonstration
Presenter: Haraguchi K.
Name of Society: WHO WP Regional Workshop: Health Sector Involvement in Implementation of the Minamata Convention on Mercury. Minamata, Japan (June 2017)

Research Lecture
Human Biomonitoring for Mercury?state of the art
Presenter: Haraguchi K.
Name of Society: WHO SE Regional Workshop: Health Sector Involvement in Implementation of the Minamata Convention on Mercury. Bangkok, Thailand (June 2017)

Research Presentation
Development of human hair reference material supporting biomonitoring of methylmercury
Presenter: Haraguchi K., Sakamoto M., Yamamoto M., Matsuyama A., Hung D.T., Yamakawa A., Sano T., Yoshinaga J.
Name of Society: 13th ICMGP. Providence, USA (July 2017)

Research Presentation
Development of human hair reference material supporting biomonitoring of methylmercury
Presenter: Haraguchi K., Sakamoto M., Yamamoto M., Matsuyama A., Hung D.T., Yamakawa A., Sano T., Yoshinaga J.
Name of Society: The Japan Society for Analytical Chemistry. Tokyo, Japan (July 2017)

Research Lecture
Analytical indicators, risks and benefits of monitoring and analysis
Presenter: Haraguchi K.
Name of Society: International Seminar of Mercury. Montevideo, Uruguay (March 2017)

Research Lecture
Mercury in the environment and its effects on health. Case of Minamata
Presenter: Haraguchi K.
Name of Society: International Seminar of Mercury. Montevideo, Uruguay (March 2017)

Research Presentation
Simple determination of methylmercury using dithizone extraction/TLC TDA AAS method
Presenter: Haraguchi K., Matsuyama A., Akagi H.
Name of Society: The Japan Society for Analytical Chemistry. Sapporo, Japan (September 2016)

Research Lecture
Technical transfer and cooperation for mercury analysis from Minamata
Presenter: Haraguchi K.
Name of Society: JICA Volunteers Meeting, Kumamoto, Japan (December 2016)

Research Presentation
Simple determination of monomethyl mercury using dithizone extraction/TLC TDA AAS method
Presenter: Haraguchi K., Matsuyama A., Akagi H.
Name of Society: 12th ICMGP. Jeju, Korea (June 2015)

Research Lecture
Development of a simple method for the determination of monomethyl mercury in least developed countries
Presenter: Haraguchi K., Matsuyama A.
Name of Society:.Parea , Kumamoto, Japan (July 2015)

[Patents]
UPA P2010-51292A
Method of culturing attached algae
Presenter: Yamamoto, T., Haraguchi K., Himeno S.

UPA P2007-120992A
Oxygen consumption rate measuring device on the seafoor
Presenter: Haraguchi K.

UPA P2007-143494A(Patent No.4444914)
Aerobic decomposition device of organic matter
Presenter: Haraguchi, K, Tawara M., Katayama T.

Education and Work experience
[Education]
  • Kagoshima University (B.A.)
  • Tohoku University (M.A.)
  • Tohoku University (Ph.D.)
[Work experience]
  • Kumamoto Prefectural University, Research Assistant.
  • Hiroshima University. Researcher.
  • Hiroshima University. Research assistant.
  • Mie Industry Enterprise Support Center. JST Project Researcher.
  • Tohoku University. Technical assistant.
  • National Institute for Minamata Disease. Research Assistant.