The NIMD Forum 2025 was held on September 27-28, 2025. The event was conducted in a hybrid format, combining in-person attendance with online participation. Over the two days, approximately 40 participants attended in person, while around 150 joined online (27th: 81 participants, 28th: 72 participants), with attendees from various countries. At this forum, 13 presentations were delivered by leading researchers from Germany, Canada, Nigeria, Indonesia, and Japan. These presentations covered new simplified methods for mercury analysis, assessments of the health impacts of mercury, other heavy metals, and plastic additives on the human body, and related policy and regulatory frameworks, all aimed at enhancing understanding and addressing the core themes. Through this forum, we were able to share insights on the importance of continuous mercury monitoring and the formulation of effective policies and countermeasures against hazardous chemicals. At the conclusion of the forum, one of the fetal-type Minamata disease patients gave a presentation, and we believe all participants shared a strong resolve to ensure the tragedy of Minamata disease is never repeated anywhere in the world.