トップ　＞　組織の案内　＞　環境・保健研究部
坂本　峰至　（さかもと　みねし）
主席研究員
環境・疫学研究部　保健研究部 　主任研究員
専門：環境疫学、毒性神経行動学

一貫し、メチル水銀の胎児影響に関する研究を行ってきた。現在は、平成27年度から5年計画で
①妊婦・胎児のメチル水銀とその他の重金属曝露評価に関する研究
②セレンによるメチル水銀毒性抑制及びセレンと水銀のヒトや 海洋生物での存在形態に関する研究、を行っている。
ＷＨＯ等関係の海外調査にも多数参加。他に、
1. 客員教授：ブラジル、パラ西部連邦大学、熊本県立大学 客員准教授：熊本大学大学院医学教育部　(平成21年-) 　非常勤講師：三重大学医学系研究科・医学部
2. Visiting Professor:
3. Editorial Board Member; Environmental Research (2014-)
4. Pan-Amazonian Journal of Health (2009-)
5. Steering Committee Member; 国際水銀会議 (2007-). を行っている。
写真は平成20年2月モンゴル国ホンゴル村に於ける環境汚染に関する水銀曝露評価調査の様子。




今年の研究テーマ・担当業務
  • メチル水銀の胎児影響及び水銀の共存元素に関する研究（RS-17-07）（代表）
  • 国際共同研究事業の推進（CT-17-06）（代表）
  • NIMDフォーラム及びワークショップ（CT-17-07）（代表）
  • 科研費基盤研究（C）「水俣湾埋立地に眠るヘドロ中水銀の化学形態別分析によるリスク　評価」（代表）
  • 動物倫理安全等委員会・COI委員会・コンプライアンス委員会
所属している研究グループ 
曝露・影響評価グループ、国際貢献グループ
主な研究業績
原著論文及び筆書

2017
  • Sakamoto M, Kakita A, Domingo JL, Yamazaki H, Oliveira R, Sarrazine S, Eto K, Murata K. (2017) Stable and episodic/bolus patterns of methylmercury exposure on mercury accumulation and histopathologic alterations in the nervous system. Environ Res. 2017 Jan;152:446-453.
  • Ha E, Basu N, Bose-O'Reilly S, Dorea JG, McSorley E, Sakamoto M, Chan HM (2017). Current progress on understanding the impacts of mercury on human health. Environ Res. 2017 Jan;152:419-433.
  • Ser PH, Omi S, Shimizu-Furusawa H, Yasutake A, Sakamoto M, Hachiya N, Konishi S, Nakamura M, Watanabe C. (2017) Differences in the responses of three plasma selenium-containing proteins in relation to methylmercury-exposure through consumption of fish/whales. Toxicol Lett. 2017 Feb 5;267:53-58.
  • 坂本峰至, 板井啓明, 村田勝敬: メチル水銀の胎児期曝露影響－水俣病から環境保健学研究へ－. 日本衛生学会誌 総説（in press）

2016
  • Sakamoto M, Murata K, Domingo JL, Yamamoto M, Oliveira RB, Kawakami S, Nakamura M: Implications of mercury concentrations in umbilical cord tissue in relation to maternal hair segments as biomarkers for prenatal exposure to methylmercury. Environ. Res., 2016; 149: 282-287.
  • Iwata T, Takaoka S, Sakamoto M, Maeda E, Nakamura M, Liu XJ, Murata K: Characteristics of hand tremor and postural sway in patients with fetal-type Minamata disease. J. Toxicol. Sci., 2016; 41: 757-763.
  • 苅田香苗，坂本峰至，吉田　稔，龍田　希，仲井　邦彦，岩井美幸，岩田豊人，前田恵理，柳沼　梢，佐藤　洋，村田勝敬: メチル水銀，水銀およびセレンに関する研究動向―疫学研究を中心に―. 日本衛生学会誌 2016; 71: 236-251.

2015
  • Sakamoto M, Itai T, Yasutake A, Iwasaki T, Yasunaga G, Fujise Y, Nakamura M, Murata K, Man Chan H, Domingo JL, Marumoto M.(2015) Mercury speciation and selenium in toothed-whale muscles. Environ Res. 2015 Nov;143(Pt A):55-61.
  • Sakamoto M, Chan HM, Domingo JL, Oliveira RB, Kawakami S, Murata K. (2015) Significance of fingernail and toenail mercury concentrations as biomarkers for prenatal methylmercury exposure in relation to segmental hair mercury concentrations. Environ Res. 2015 Jan; 136:289-94.

2014
  • Ilmiawati C, Yoshida T, Itoh T, Nakagi Y, Saijo Y, Sugioka Y, Sakamoto M, Ikegami A, Ogawa M, Kayama F. (2014) Biomonitoring of mercury, cadmium, and lead exposure in Japanese children: a cross-sectional study. Environ Health Prev Med. 2014 Oct 8.
  • Nakamura M, Hachiya N, Murata KY, Nakanishi I, Kondo T, Yasutake A, Miyamoto K, Ser PH, Omi S, Furusawa H, Watanabe C, Usuki F, Sakamoto M.(2014) Methylmercury exposure and neurological outcomes in Taiji residents accustomed to consuming whale meat. Environ Int. 2014 Jul; 68:25-32.
  • Yamamoto M, Yanagisawa R, Motomura E, Nakamura M, Sakamoto M, Takeya M, Eto K. (2014) Increased methylmercury toxicity related to obesity in diabetic KK-Ay mice. J Appl Toxicol. 2014 Aug; 34(8):914-23.
  • Arai K, Maeda E, Iwata T, Tanaka O, Murata K and Sakamoto M. (2014) Impact of dietary behaviors on dyslipidemia in Japanese male workers. Ann Transl Med Epidemiol. 2014; 1(1):1003.
  • 坂本峰至、村田勝敬 (2014). 第2章 地球規模での水銀汚染と生体影響. 水銀に関する水俣条約と最新対策・技術. 高岡昌輝 監修. シーエムシー出版. pp15-22. 2014 Nov.
  • 臼杵扶佐子、坂本峰至.（2014） 胎児におけるメチル水銀中毒症. 神経症候群（第2版）IV－その他の神経疾患を含めて－. 日本臨牀 819-822. 09, 2014.

2013
  • Horvat M,Sakamoto M, Chan L, Faganeli J. Mercury in contaminated sites: identification, characterisation, impacts, and remediation. Environ Res. 2013 Aug;125:1.
  • 坂本峰至、村田勝敬(2013). 水銀の毒性―汚染の歴史と研究の現状―. 環境技術. 2013 Oct;42(10):584-589.
  • Sakamoto M, Yasutake A, Domingo JL, Chan HM, Kubota M, Murata K (2013) . Relationships between trace element concentrations in chorionic tissue of placenta and umbilical cord tissue: Potential use as indicators for prenatal exposure. Environ Int. 2013 Sep 9;60C:106-111.（JSPS KAKENHI Grant Number 23510085）
  • Sakamoto M, Yasutake A, Kakita A, （他6名） (2013) Selenomethionine protects against neuronal degeneration by methylmercury in the developing rat cerebrum. Environ Sci Technol. 2013 Mar 19; 47(6):2862-8. （JSPS KAKENHI Grant Number 23510085）
  • 坂本峰至、山元 恵(2013) 食品中の微量元素 必須元素から放射能核種まで　水銀（メチル水銀）. 日本食品衛生協会　編. 2013.04.01

2012
  • Sakamoto M, Murata K, Kakita A, Sasaki M (2012) A review of mercury toxicity with special reference to methylmercury, in：Advances in Environmental Chemistry and Toxicology of Mercury (Cai Y, Liu G, O'Driscoll N eds.), Wiley-VCH (Weinheim), pp. 501-516 Chapter 15.
  • Sakamoto M, (他3名) (2012) Mercury and docosahexaenoic acid levels in maternal and cord blood in relation to segmental maternal hair mercury concentrations at parturition. Environ Int 44：112-117
  • Sakamoto M, (他4名) (2012) Changes in body burden of mercury, lead, arsenic, cadmium and selenium in infants during early lactation in comparison with placental transfer. Ecotox Environ Safety 84: 179-184

2011
  • 坂本峰至、安武 章: 魚介類とメチル水銀について. モダンメディア. 57(3), 16-21, 2011.
  • Steckling N, Boese-O'Reilly S, Sakamoto M, (他16名).Mercury exposure in female artisanal small-scale gold miners (ASGM) in Mongolia: An analysis of human biomonitoring (HBM) data from 2008. Sci Total Environ. 2011 Feb 1; 409(5):994-1000.
  • Murata K, Sakamoto M. Minamata disease.In: Nriagu JO(ed.) Encyclopedia of Environmental Health, vol 3:774-780, Burlington: Elsevier.
  • Murata K, Yoshida M, Sakamoto M, Iwai-Shimada M, Yaginuma-Sakurai K, Tatsuta N, Iwata T, Karita K, Nakai K. Recent evidence from epidemiological studies onmethylmercury toxicity. Nihon Eiseigaku Zasshi. 2011 Sep;66(4):682-95. Review.
  • Mahaffey KR, Sunderland EM, Chan HM, Choi AL, Grandjean P, Marien K, Oken E, Sakamoto M, Schoeny R, Weihe P, Yan CH, Yasutake A. Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption. Nutr Rev. 2011 Sep;69(9):493-508.

2010
  • Sakamoto M (1st), Murata K, Tsuruta K, (他2名). Retrospectve study on temporal and regional variations of methylmercury concentrations in preserved umbilical cords collected from inhabitants of the Minamata area, Japan Ecotoxicol Environ Saf. 73 (2010), 1144-1149.
  • Sakamoto M (1st), Murata K, Kubota M, (他2名). Mercury and heavy metal profiles of maternal and umbilical cord RBCs in Japanese population. Ecotoxicol Environ Saf. 2010 ;73(1):1-6.
  • 村田勝敬、坂本峰至、佐藤　洋: メチル水銀曝露の多様性と健康リスク、特集；環境リスク、公衆衛生 Vol 74, 279-283, 2010.
  • 坂本峰至: メチル水銀. 食品安全ハンドブック、食品安全編集委員会編、丸善, 118-120, 2010.
  • 坂本峰至、佐々木眞敬: メチル水銀.　広範囲血液・尿化学検査、免疫学的検査(2)－その数値をどう読むか－、日本臨床.　68巻増刊号 1, 576-580, 2010.
  • 坂本峰至、山本 恵: 微量元素をめぐる動向3　水銀（メチル水銀）. 食品衛生研究. 60巻12号, 35-41, 2010.

2009
  • Sakamoto M, Murata K, Kubota M, Nakai K, Satoh H. Mercury and heavy metal profiles of maternal and umbilical cord RBCs in Japanese population. Ecotoxicol Environ Saf. 2010 Jan;73(1):1-6. Epub 2009 Oct 12.
  • Cheng J, Gao L, Zhao W, Liu X, Sakamoto M, Wang W. Mercury levels in fisherman and their household members in Zhoushan, China: impact of public health. Sci Total Environ. 407(8):2625-30. (2009)
  • Cheng J, Yang Y, Ma J, Wang W, Liu X, Sakamoto M, Qu Y, Shi W. Assessing noxious effects of dietary exposure to methylmercury, PCBs and Se coexisting in environmentally contaminated rice in male mice.Environ Int. 35(3):619-25. (2009)

2008
  • Sakamoto M, Kubota M, Murata K, Nakai K, Sonoda I, Satoh H. Changes in mercury concentrations of segmental maternal hair during gestation and their correlations with other biomarkers of fetal exposure to methylmercury in the Japanese population. Environ Res. 106(2):270-6 (2008)
  • Carratù MR, Coluccia A, Modafferi AM, Borracci P, Scaccianoce S, Sakamoto M, Cuomo V. Prenatal methylmercury exposure: effects on stress response during active learning. Bull Environ Contam Toxicol. 81(6):539-42. (2008)
  • Liu X, Cheng J, Song Y, Honda S, Wang L, Liu Z, Sakamoto M, Liu Y. Mercury concentration in hair samples from Chinese people in coastal cities. J Environ Sci (China). 2008;20(10):1258-62.
  • Li P, Feng X, Qiu G, Li Z, Fu X, Sakamoto M, Liu X, Wang D. Mercury exposures and symptoms in smelting workers of artisanal mercury mines in Wuchuan, Guizhou, China. Environ Res. 107(1):108-14. (2008)
  • Carratu MR, Coluccia A, Modafferi AM, Borracci P, Scaccianoce S, Sakamoto M, Cuomo V. Prenatal methylmercury exposure: effects on stress response during active learning. Bull Environ Contam Toxicol. 2008 Dec;81(6):539-42.

2007
  • Sakamoto M, Kaneoka T, Murata K, Nakai K, Satoh H. Akagi H. Correlations between mercury concentrations in umbilical cord tissue and other biomarkers of fetal exposure to methylmercury in the Japanese population. Environ Res. 103(1):106-11 (2007).
  • Sakamoto M, Feng X, Li O, Qiu G, Jiang H, Yoshida M, Iwata T, Liu XJ, Murata K. High exposure of Chinese mercury mine workers to elemental mercury vapor and increased methylmercury levels in their hair. Environ Health Prev Med 12(2):66-70 (2007)
  • Coluccia A, Borracci P, Giustino A, Sakamoto M, Carratù MR. Effects of low dose methylmercury administration during the postnatal brain growth spurt in rats. Neurotoxicology and Teratology 29 (2): 282-287 (2007)
  • 劉　暁潔、坂本　峰至、加藤　たけ子、岡本　美和子、有村　公良　胎児性水俣病患者の現在のActivity of Daily Living (ADL) 実態と15年前との比較およびコミュニケーション障害に関する研究　日本衛生学雑誌905-910 (2007)
  • Mergler D, Anderson A H, Chan LHM, Mahaffey KR., Murray M, Sakamoto M, Stern A H. Methylmercury Exposure and Health Effects in Humans: A Worldwide Concern. The Panel on Health Risks and Toxicological Effects of Methylmercury: AMBIO 3-11 (2007).
  • Ohno T, Sakamoto M, Kurosawa T, Dakeishi M, Iwata T, Murata K. Total mercury levels in hair, toenail, and urine among women free from occupational exposure and their relations to renal tubular function. Environ Res. 103(2):191-7 (2007).
  • Iwata T, Sakamoto M, Feng X, Yoshida M, Liu XJ, Dakeishi M, Li P, Qiu G, Jiang H, Nakamura M, Murata K. Effects of mercury vapor exposure on neuromotor function in Chinese miners and smelters. Int Arch Occup Environ Health 70 (5): 381-387 (2007)

2006
  • Vu Duc Loi, Le Lan Anh, Trinh Anh Duc, Trinh Xuan Gian, Pham Gia Mon, Tran Van Huy, Nguyen Quoc Thong, Alian Boudou, Sakamoto M, Dao Van Bay. Contamination by cadmium and mercury of the water, sediment and biological component of hydrosystems around Hanoi. J Chemistry 44, 382-386 (2006)
  • 坂本　峰至、赤木　洋勝　無機・有機水銀（水環境ハンドブック）日本水環境学会　朝倉書店　352-355 (2006)
  • Honda S, Hylander L, Sakamoto M. Recent advances in evaluation of health effects on mercury with special reference to methylmercury-A Minireview. Environ Health Prev Med 11(4): 171-176 (2006).
  • Iwata T, Nakai K, Sakamoto M, Dakeishi M, Satoh H, Murata K. Factor affecting hand tremor and postural sway in children. Environ Health Prev Med 11(1):17-23 (2006).

2005
  • Sakamoto M, Murata K, Nakai K, Satoh H. Difference in methylmercury exposure to fetus and breast-feeding offspring: a mini-review. Kor J Env Hlth 31, 179-186 (2005).
  • Sakamoto M, Yasutake A, Satoh H. Methylmercury exposure in general populations of Japan, Asia and Oceania. Dynamics of mercury pollution on regional and global scales: atmospheric processes and human exposures around the world. N. Pirrone & K.R. Mahaffey (Eds) Springer (2005) p125-146.
  • Dakeishi M, Nakai K, Sakamoto M, Iwata T, Suzuku K, Liu X, et al. Effects of hair treatment on hair mercury - The best biomarker of methylmer5cury exposure? Environ Health Prev Med 10(4):208-212 (2005).
  • Murata K, Sakamoto M, Nakai K, Dakeishi M, Iwata T, Liu XJ, et al. Subclinical effects of prenatal methylmercury exposure on cardiac autonomic function in Japanese children. Int Arch Occup Environ Health:1-8.(2005)
  • 坂本　峰至、赤木　洋勝　水銀の毒性と健康影響　廃棄物学会誌16 185-190 (2005).
  • Pan HS, Sakamoto M, Liu XJ, Futatsuka M. Deficits in rat brain growth induced by methylmercury treatment during the brain growth spurt. J Health Sci 51(1) 1-7 (2005).

2004
  • Murata K, Sakamoto M, Nakai K, Weihe P, Dakeishi M, Iwata T, Liu XJ, Ohno T, Kamiya K, Satoh H. Effects of methylmercury on neurodevelopment in Japanese children in relation to Madeiran study. Int Arch Occup Environ Health 77, 571-579. (2004)
  • 坂本　峰至、赤木　洋勝　メチル水銀（広範囲血液・尿化学検査・免疫学的検査－その数値をどう読むか－）　日本臨床62巻増刊号12 (2004) 529-532.
  • 坂本　峰至、衞藤　光明　成人においても微量のメチル水銀は危険なのか？医学のあゆみ 211, 1155-1156. (2004)
  • Sakamoto M, Kakita A, Oliveira RB, Pan HS, Takahashi H. Dose-dependent effects of methylmercury administered during neonatal brain spurt in rats. Dev Brain Res152, 171-176. (2004)
  • Sakamoto M, Kubota M, Liu XJ, Murata K, Nakai K, Satoh H. Maternal and fetal mercury and n-3 polyunsaturated fatty acids as a risk and benefit of fish consumption to fetus. Environ Sci Technol 38, 3860-3863. (2004)
  • Sakamoto M, Kubota M. Plasma fatty acid profiles in 38 pairs of maternal and umbilical cord blood samples. Environ Health & Prev Med 9, 67-69. (2004)
  • Pan HS, Sakamoto M, Oliveira RB, Liu XJ, Kakita A, Futatsuka M. Changes in methylmercury accumulation in the brain of rat offspring throughout gestation and during suckling. Toxicol Environ Chem 86, 163-170. (2004)
  • Nakai K, Suzuki K, Oka T, Murata K, Sakamoto M, Okamura K, HosokawaT, Sakai T, Nakamura T, Saitoh Y, Kurokawa N, Kameo S, Satoh H. A Cohort study of effects of perinatal exposures to methylmercury and environmentally persistent organic pollutants on neurobehavioral development in Japanese children. Tohoku J Exp Med 202, 227-237. (2004)
  • Sakamoto M, Kubota M, Matsumoto S, Nakano A, Akagi H. Declining risk of methylmercury exposure to infants during lactation. Environ Res (2003) 90 (3), 185-189.

2003
  • Kakita A, Inenaga C, Sakamoto M, Takahashi H. Neuronal migration disturbance and consequent cyoarchitecture in the cerebral cortex following transplacental administration of methylmercury. Acta Neuropathol 104 (4), 409-417. (2003)
  • Kakita A, Inenaga C, Sakamoto M, Takahashi H. Disruption of postnatal progenitor migration and consequent abnormal pattern of glial distribution in the cerebral cortex following administration of methylmercury. J Neuropathol Exp Neurol 62 (8), 835-847. (2003)
  • Iwasaki Y, Sakamoto M, Nakai K, Oka T, Deshimaru M, Iwata T, Satoh H, Murata K. Estimation of daily mercury intake from seafood in Japanese women: Akita Cross-Sectional Study. Tohoku J Exp Med200, 67-73. (2003)

2002
  • Sakamoto M, Kubota M, Matsumoto S, Nakano A, Akagi H. Declining risk of methylmercury exposure to infants during lactation. Environ Res (2002) 90, 185-189.
  • Sakamoto M, Kakita A, Wakabayashi K, Takahashi H, Nakano A, Akagi H. Evaluation of changes in methylmercury accumulation in the developing rat brain and its effects: a study with consecutive and moderate dose exposure throughout gestation and lactation periods. Brain Res (2002) 949, 51-59.
  • Kakita A, Inenaga C, Sakamoto M, Takahashi H. Neuronal migration disturbance and consequent cytoarchitecture in the cerebral cortex following transplacental administration of methylmercury. Acta Neuropathol (2002) 104, 409-417.

2001
  • Sakamoto M, Nakano A, Akagi H. Declining minamata male birth ratio associated with increased male fetal death due to heavy methylmercury pollution. Environ Res Section A (2001) 87, 92-98.
  • Kakita A, Wakabayashi K, Su M, Sakamoto M, Ikuta F, Takahashi H. Intrauterine methylmercury intoxication: pattern of neuronal degeneration in the fetal brain and consequence on higher brain function in maturity. In: Takizawa Y and Osame M (eds.), Understanding of Minamata Disease. Methylmercury Poisoning in Minamata and Niigata, Japan. The Japan Public Health Association, Tokyo, (2001) pp.85-93.

2000
  • Kakita A, Wakabayashi K, Su M, Yoneoka Y, Sakamoto M, Ikuta F, Takahashi H. Intrauterine methylmecury intoxication Consequence of the inherent brain lesions and cognitive dysfunction in maturity. Brain Res (2000) 877, 322-330.
  • Kakita A, Wakabayashi K, Su M, Sakamoto M, Ikuta F, Takahashi H. Distinct pattern of neuronal degeneration in the fetal rat brain induced by consecutive transplacental administration of methylmercury. Brain Res (2000) 859, 233-239.

1999
  • 坂本　峰至. 海を渡った産業廃棄物－カンボジアで見たもの－ 産廃処理の総合専門誌 INDUST　No.142 36-38. (1999)
  • Fukuda Y, Ushijima K, Kitano T, Sakamoto M, Futatsuka M. An analysis of subjective complaints in a population living in a methylmercury-polluted area. Environ Res Section A81, 100-107. (1999)

1998
  • Sakamoto M, Wakabayashi K, Kakita A, Takahashi H, Adachi T, Nakano A. Widespread neuronal degeneration in rats following oral administration of methylmercury during the postnatal developing phase: a model of fetal-type Minamata Disease. Brain Res 784, 351-354. (1998)
  • Oyama Y, Nakata M, Sakamoto M, Chikahisa L, Miyoshi N, Satoh M. Methylmercury toxicity in dissociated rat brain neurons: modification by L-cysteine and trimethylbenzylmercaptan and comparison with dimethylmercury and N-ethylmaleimide. Environ Toxicol & Pharmacol (1998)6, 221-227.

1997
  • Okazaki E, Oyama Y, Chikahisa L, Nagano T, Katayama N, Sakamoto M. Fluorescent estimation on cytotoxicity of methylmercury in dissociated cerebellar neurons: its comparison with ionomycin. Environ Toxicol Pharmacol3, 237. (1997)

1996
  • Sakamoto M, Ikegami N, Nakano A. Protective Effects of Ca2+ Channel Blockers against Methyl Mercury Toxicity. Pharmacol & Toxicol78, 193-199. (1996)
  • 坂本　峰至、中野　篤浩、赤木　洋勝. 赤血球中水銀濃度の意味－メチル水銀汚染指標から魚介類摂取量指標へ－FFI JOURNAL No.167 109-115. (1996)

1995
  • Sakamoto M, Nakano A. Comparison of mercury accumulation among the brain, liver, kidney, and the brain regions of rats administered methylmercury in Various Phases of Postnatal Development. Bull Environ Contam Toxicol 55, 588-596. (1995)
  • Wakabayashi K, Kakita A, Sakamoto M, Su M, Iwanaga K, Ikuta F. Variability of brain lesions in rats administered methylmercury at various postnatal development phases. Brain Res705, 267-272. (1995)

1993
  • 坂本　峰至、中野　篤浩、赤木　洋勝 北野　隆雄、二塚　信. 赤血球中水銀濃度における性、年齢差. 日本衛生学雑誌 第48巻 第5号 911-919. (1993)
  • Sakamoto M, Nakano A, Kajiwara Y, Naruse I, Fujisaki T. Effects of methyl mercury in postnatal developing rats. Environ Res61, 43-50. (1993)
  • Kinjo Y, Higashi H, Nakano A, Sakamoto M, Sakai R. Profile of Subjective Complaints and Activities of Daily Living among Current Patients with Minamata Disease after 3 Decades. Environ Res 63, 241-251. (1993)

1992
  • 坂本　峰至、中野　篤浩、金城　芳秀、若宮　純司、藤崎　正、東　博文、北野　隆雄、二塚　信.一般住民検診における過酸化脂質値（血漿TBA値）についての断面研究. 日本公衆衛生雑誌 (1992) 第39巻 第7号 399-409.
1991
  • Sakamoto M, Nakano A, Kinjo Y, Higashi H, Futatsuka M. Present mercury levels in red blood cells of nearby inhabitants about 30 years after the outbreak of Minamata Disease. Ecotoxicology and Environmental Safety, (1991)22, 58-66.
  • Kinjo Y, Nakano A, Sakamoto M, Futatsuka M, Kato H. Clarification of mortality patterns among Minamata Disease patients. Environ Sci (1991)1,2, 73-88.
  • 金城　芳秀、中野　篤浩、坂本　峰至、渡邊　正夫、二塚　信、加藤　寛夫. 水俣病認定患者の死亡構造に関する追跡調査研究－死亡率および標準化死亡比（SMR）による検討－ 保健の科学 (1991) 第33巻 第8号579-583.

1990
  • 坂本　峰至、中野　篤浩、金城　芳秀、東　博文、二塚　信. 一般健康診査における愁訴と動脈硬化指数との関連性. 民族衛生 (1990) 第56巻 第2号 87-96.
  • 清水　利之、東　博文、高瀬　千義、坂本　峰至. Fitness Analyzer BFT-2000による体脂肪測定方法の検討. 保健の科学 (1990) 第32巻 第12号 848-849.
  • Nakamura K, Sakamoto M, Uchiyama H, Yagi O. Organomercurial-volatilizing bacteria in the mercury-polluted sediment of Minamata Bay, Japan. Appl & Environ Microbiology (1990)56 (1), 304-305.
  • Wakisaka I, Yanagihashi T, Nakano A, Sakamoto M.　Interaction of sulfur dioxide and nicotine aerosol as sensory irritants. 鹿児島大学医学雑誌 (1990) 第42巻 第1号 59-67.

1989
  • 安藤　哲夫、柳橋　次雄、脇阪　一郎、坂本　峰至. メチル水銀投与ラットにおける脂質過酸化および脂肪酸組成. 日本衛生学雑誌 (1989) 第44巻 第5号 993-1001.
  • 安藤　哲夫、脇阪　一郎、柳橋　次雄、坂本　峰至. ラットにおけるメチル水銀投与と脂質過酸化. 日本衛生学雑誌 (1989) 第44巻 第3号 733-738.

1988
  • 坂本　峰至、脇阪　一郎、安藤　哲夫、柳橋　次雄. ラットの組織における脂質過酸化及び水銀の蓄積に及ぼす食餌性脂質の影響. 日本衛生学雑誌 (1988) 第43巻 第4号 917-922.
  • 安藤　哲夫、脇阪　一郎、柳橋　次雄、坂本　峰至. ラットにおける水銀の蓄積および排泄に及ぼすエタノールの影響. 日本衛生学雑誌 (1988) 第43巻 第3号 717-723.

1987
  • Ando T, Sakamoto M, Yanagihashi T. Effect of methylmercury on the lipid components in rats. Acta Med Univ Kagoshima (1987)29 (2), 67-74.

1986
  • 坂本　峰至. メチル水銀中毒に及ぼす食餌性脂質の影響. 日本衛生学雑誌 (1986) 第40巻 第6号 903-909.

1985
  • 坂本　峰至. 喫煙者及び非喫煙者の呼気中のエタン量. 日本衛生学雑誌 (1985) 第40巻 第5号 835-840.
  • Kanazawa A, Teshima S, Sakamoto M. Effect of dietary lipids, fatty acids, and phospholipids on growth and survival of prawn (penaeus japonicus) larvae. Aquaculture (1985)50, 39-49.

1984
  • Sakamoto M. Effect of methylmercury on the lipid composition in guinea pigs. Industrial Health (1985)23, 171-179.
  • 脇阪　一郎、柳橋　次雄、泊　惇、安藤　哲夫、坂本　峰至. 桜島火山活動が死亡像にあたえる影響. 日本公衆衛生誌 (1984) 第31巻 第10号 548-556.

1982
  • Sakamoto M, Holland DL, Jones DA. Modification of the nutritional composition of Artemia by incorporation of polyunsaturated fatty acids using micro-encapsulated diets. Aquaculture (1982)28, 311-320.
  • Kanazawa A, Teshima S, Sakamoto M. Requirements of essential fatty acids for the larval Ayu. Bull Jap Soc Sci Fisheries (1982)48 (4), 587-590.
  • Teshima S, Kanazawa A, Sakamoto M. Essential fatty acids of Tilapia nilotica. Mem. Fac. Fish., Kagoshima Univ (1982)31, 201-204.

1981
  • Teshima S, Kanazawa A, Sakamoto M. Attempt to culture the rotifers with microencapsulated diets.　 Bull Jap Soc Sci Fisheries (1981)47 (12), 1575-1578.

1980
  • Kanazawa A, Teshima S, Sakamoto M, Shinomiya A. Nutritional requirements of the puffer fish: purified test diet and the optimum protein level. Bull Jap Soc Sci Fisheries (1980)46 (11), 1957-1961.
  • Kanazawa A, Teshima S, Sakamoto M, Md. Awal A. Requirements of Tilapia zillii for essential fatty acids.　 Bull Jap Soc Sci Fisheries (1980)46 (11), 1353-1356.
外部資金による研究
  • 胎児期に受けたメチル水銀の神経系及び生理的老化に及ぼす後影響に関する研究（科研費）
  • 発達期脳へのメチル水銀毒性に関する食物由来セレン化合物の抑制機構に関する研究（科研費）
主な履歴、学歴、学位、表彰等
医学博士、日本衛生学会編集委員 (3年間、平成17-19)、日本衛生学会　評議員（平成17年から）、国際水銀学会運営委員（平成20年から）、農水省研究評価委員（平成20-22年）